Platelet cold agglutinins.
نویسندگان
چکیده
A “cold” platelet agglutinin is described reacts only at temperatures below 34#{176}C. which is present in plasma and serum, It agglutinates homologous and autois greater than 100,000 in molecular logous platelets but appears to have no weight, appears to be a protein of the imeffect on in vivo platelet function. It is munoglobulin type, is adsorbed by plateseen in patients with systemic disease and lets in the absence of bivalent cations, and can cause spuriously low platelet counts. T HE PURPOSE of this report is to describe a phenomenon of platelet ag-
منابع مشابه
Problems of Cold Agglutinins in Cardiac Surgery: How to Manage Cardiopulmonary Bypass and Myocardial Protection
Cold agglutinins are of unique relevance in cardiac surgerybecause of the use of hypothermic cardiopulmonary bypass (CPB). Cold autoimmune diseases are defined by the presence of abnormal circulating proteins (usually IgM or IgA antibodies) that agglutinate in response to a decrease in body temperature. These disorders include cryoglobulinemia and cold hemagglutinin disease.Immunoglobulin M aut...
متن کاملA Study on Cold Agglutinins in Malaria from a Tertiary Care
Background: Malarial infection associated with common hematological abnormalities like anemia, Thrombocytopenia, Hemolytic anemia. Hemolytic anemia is due to occurrence of cold agglutinins. This study throws light on the prevalence of cold agglutinins in patients with malarial infection and their detection. Method: About 150 patients diagnosed as having Malaria by Peripheral smear, QBC for mala...
متن کامل70-year old female patient with mismatch between hematocrit and hemoglobin values: the effects of cold agglutinin on complete blood count
INTRODUCTION There are a number of pre-analytical and analytical factors, which cause false results in the complete blood count. The present case identifies cold agglutinins as the cause for the mismatch between hematocrit and hemoglobin values. MATERIALS AND METHODS 70-year old female patient had a history of cerebrovascular diseases and rheumatoid arthritis. During routine laboratory examin...
متن کاملLeukoagglutination reported as platelet clumps.
Blood cell count was performed on an automated analyzer using an ethylenediaminetetraacetic acid (EDTA) blood specimen and showed normal hemoglobin and leukocytes (7.2 109/L), but a mild thrombocytosis (467 109/L). Platelet clumps were flagged by the cell counter. However, when the peripheral smear was reviewed, there was leukocyte agglutination (shown, left) rather than clumps of platelets. Th...
متن کاملAtypical lymphocytosis, cold agglutinin hemolytic anemia, and monoclonal gammopathy in an HIV patient with marrow involvement by diffuse large B-cell lymphoma.
A 43-year-old man presented with fever, fatigue, and shortness of breath. Physical examination revealed bilateral axillary lymphadenopathy. Complete blood count showed hemoglobin of 9.8 g/dL, a white cell count of 4.4 3 10/L, and a platelet count of 195 3 10/L. Blood smear showed increased red blood cell agglutination, polychromasia with nucleated red cells, and atypical lymphocytosis (panel A)...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Blood
دوره 36 2 شماره
صفحات -
تاریخ انتشار 1970